ARTYKUŁ PRZEGLĄDOWY
Wpływ witaminy D3 na zdrowie jamy ustnej

Infl uence of vitamin D3 on oral health

Wiktoria Musyt, Filip Podgórski, Kacper Nijakowski

Streszczenie
Witamina D3 jest hormonem steroidowym, który odgrywa ważną rolę w regulacji homeostazy całego organizmu, a jej defi cyty mogą manifestować się również w obrębie jamy ustnej. U dzieci niedobory witaminy D3 mogą prowadzić do zaburzeń mineralizacji zębów, a tym samym do defektów w obrębie szkliwa i zębiny, a także do zwiększenia podatności na próchnicę. Niedobory witaminy D3 wpływają negatywnie na procesy gojenia i regeneracji tkanek przyzębia oraz nasilają przebiegające w nich procesy zapalne. Suplementacja witaminy D3 pozwala zwiększyć szansę powodzenia zabiegów regeneracyjnych w obrębie tkanek przyzębia. Ponadto witamina D3 może modulować przebieg chorób nowotworowych obszaru głowy i szyi poprzez regulację procesów apoptozy czy proliferacji w komórkach nowotworowych, co prowadzi do zahamowania wzrostu nowotworu. Niniejszy przegląd piśmiennictwa ma na celu przedstawienie zależności między niedoborami oraz suplementacją witaminy D3 a zdrowiem jamy ustnej.

Abstract
Vitamin D3 is a steroid hormone playing a significant role in maintaining homeostasis of the whole organism and its deficit can manifest also in the oral cavity. In children, vitamin D3 deficits can lead to disturbances in tooth mineralisation, resulting in defects within the enamel and dentin, and also increase the susceptibility to caries. Vitamin D3 defi cits have a negative impact on the healing and regeneration processes of periodontal tissues, as well as enhance the severity of infl ammatory processes. Vitamin D3 supplementation increases the odds of success in regenerative procedures within the periodontal tissues. Moreover, vitamin D3 plays a role in progression of head and neck area cancers by regulating processes, such as apoptosis and proliferation in cancer cells, leading to tumor growth inhibition. This literature review aims to present the relationship of vitamin D3 deficits and supplementation with oral health.

Hasła indeksowe: niedobór witaminy D3, zdrowie jamy ustnej, choroba przyzębia, próchnica, leczenie ortodontyczne, nowotwór jamy ustnej

Key words: vitamin D3 defi ciency, oral health, periodontal disease, caries, orthodontic treatment, oral cancer

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